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胡显镜导师简介
2023-03-31 16:48  

医学博士,副研究员,东莞市特色人才,学院高层次人才,毕业于暨南大学,香江学者计划项目获得者,暨南大学、香港浸会大学博士后。从事消化道疾病的发病机制与中医药治疗方面的基础与应用基础研究,已发表SCI学术论文30余篇,主持国家级、省市级项目8项,申请中药防治消化道疾病专利12项,4项已获授权。

联系方式:thuxj@gdmu.edu.cn

 

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发表文章(部分代表作)

[1] Xianjing Hu#, Sarwat Fatima#, Minting Chen,Tao Huang, Yuen Wa Chen, Ruihong Gong, Hoi Leong Xavier Wong, Rongmin Yu, Liyan Song, Hiu Yee Kwan*,Zhaoxiang Bian*. Dihydroartemisinin is potential therapeutics for treating late-stage CRC by targeting the elevated c-Myc level.Cell Death and Disease, 2021, 12: 1053. DOI: https://doi.org/10.1038/s41419-021-04247-w

[2] Xianjing Hu#, Sarwat Fatima#, Minting Chen#, Keyang Xu, Chunhua Huang, Rui-Hong Gong, Tao Su, Hoi Leong Xavier Wong, Zhaoxiang Bian* and Hiu Yee Kwan*. Toll-like receptor 4 is a master regulator for colorectal cancer growth under high-fat diet by programming cancer metabolism. Cell Death and Disease, 2021, 12(8): 791. DOI: https://doi.org/10.1038/s41419-021-04076-x

[3] Weibo Dai #, Chang Chen #, Huiting Feng#, Guangru Li, Weiwen Peng*, Xin Liu, Jing Yang, Xianjing Hu*. Protection of Ficus pandurata Hance against acute alcohol-induced liver damage in mice via suppressing oxidative stress, inflammation, and apoptosis. Journal of Ethnopharmacology, 2021, 275: 114140. DOI: https://doi.org/10.1016/j.jep.2021.114140

[4] Weibo Dai#, Xinyi Zhan#, Weijie Peng#, Xin Liu, Weiwen Peng*, Quanxi Mei, Xianjing Hu*. Ficus pandurata Hance inhibits ulcerative colitis and colitis-associated secondary liver damage of mice by enhancing anti-oxidation activity. Oxidative Medicine and Cellular Longevity, 2021, 2021: 2617881. DOI: https://doi.org/10.1155/2021/2617881

[5] Sarwat Fatima#, Xianjing Hu#, Chunhua Huang#, Weixiong Zhang, Jing Cai, Min Huang, Rui-Hong Gong, Minting Chen, Alan H. M. Ho, Tao Su, Hoi Leong Xavier Wong, Zhaoxiang Bian and Hiu Yee Kwan. High-fat diet feeding and palmitic acid increase CRC growth in β2AR-dependent manner. Cell Death and Disease, 2019, 10: 711. DOI: https://doi.org/10.1038/s41419-019-1958-6

[6] Xianjing Hu, Weiming Zheng, Yuanyuan Luo, Xiaozheng Ou, Liyan Song, Sirui Zhang, Tingsha He, Zhongyi Guo, Jianhua Zhu, Hui Shi, Weijuan Huang & Rongmin Yu. Arca subcrenata polypeptides inhibit human colorectal cancer HT-29 cells growth via suppression of IGF-1R/Akt/mTOR signaling and ATP production. utrition and Cancer, 2020, 72(2): 260-272. DOI: https://doi.org/10.1080/01635581.2019.1625935

[7] Weibo Dai#, Jing Yang#, Haili Cao#, Zhuqiang Wang, Guangru Li, Xiwen Zhong,Weiwen Peng, Chang Chen, Xin Liu, Congyan Zeng* and Xianjing Hu*. Clinical evidence-guided anti-rheumatoid arthritis study of Shuji tablet in adjuvant-induced arthritis rats and mechanism exploration via network pharmacological approach. Frontiers in Pharmacology, 2021 Jul 29;12: 694507. doi: 10.3389/fphar.2021.694507. eCollection 2021.

[8] Yao Wen#, Sixue Bi#, Xianjing Hu#, Jianing Yang, Chunlei Li, Hang Li, Dong Bo Yu, Jianhua Zhu*, Liyan Song*, and Rongmin Yu*. Structural characterization and immunomodulatory mechanisms of two novel glucans from Morchella importuna fruiting bodies. International Journal of Biological Macromolecules, 2021, 183: 145-157. DOI: https://doi.org/10.1016/j.ijbiomac.2021.04.084

[9] Bao Peng#, Yuanyuan Luo#, Xianjing Hu#, Liyan Song , Jianing Yang, Jianhua Zhu, Yao Wen, Rongmin Yu. Isolation, structural characterization, and immunostimulatory activity of a new water-soluble polysaccharide and its sulfated derivative from Citrus medica L. var. sarcodactylis. International Journal of Biological Macromolecules, 2019, 123: 500-511. DOI: https://doi.org/10.1016/j.ijbiomac.2018.11.113

[10] Weibo Dai#, Chang Chen#, Gengting Dong#, Guangru Li, Weiwen Peng, Xin Liu, Jing Yang, Leyu Li *, Ruiyan Xu, Xianjing Hu*. Alleviation of Fufang Fanshiliu decoction on type II diabetes mellitus by reducing insulin resistance: A comprehensive network prediction and experimental validation. Journal of Ethnopharmacology, 2022, 294: 115338. DOI: https://doi.org/10.1016/j.jep.2022.115338

[11]Xinyi Zhan#, Weijie Peng#, Zhuqiang Wang#, Xin Liu, Weibo Dai*, Quanxi Mei*, Xianjing Hu*. Polysaccharides from garlic protect against liver injury in DSS-induced inflammatory bowel disease of mice via suppressing pyroptosis and oxidative damage. Oxidative Medicine and Cellular Longevity, 2022, 2022: 2042163. DOI: https://doi.org/10.1155/2022/2042163

[12] Weibo Dai#, Jing Yang #, Xin Liu #, Quanxi Mei*,Weijie Peng, Xianjing Hu*. Anti-colorectal cancer of Ardisia gigantifolia Stapf. and targets prediction via network pharmacology and molecular docking study. BMC Complementary Medicine and Therapies, 202, 23(1): 4. DOI: 10.1186/s12906-022-03822-8.

[13] Weibo Dai#, Xiaoyan Pang#, Weiwen Peng#, Xinyi Zhan, Chang Chen, Wenchang Zhao, Congyan Zeng, Quanxi Mei, Qilei Chen, Weihong Kuang*, Zhanping Gou and Xianjing Hu*. Liver protection of a low-polarity fraction from Ficus pandurata Hance, prepared by supercritical CO2 fluid extraction, on CCl4-induced acute liver injury of mice via inhibiting apoptosis and ferroptosis mediated by strengthening anti-oxidation. Molecules, 2023, 28, 2078. DOI: 10.3390/molecules28052078

 

主持的科研项目(纵向课题)

1)广东省自然科学基金-面上项目(2023.1.1-2025.12.31

2湛江市科技发展专项基金竞争分配性项目(2022A010032022.10-2025.10

3)东莞市社会发展科技项目,2023重点项目(202318009398322024.1-2026.12

4)广东省中医药局,2023中医药专项(202411592024.1-2025.12

5)国家自然科学基金(815033032016.1-2018.12

6)香江学者计划项目(XJ20150212016.1-2019.1

7)广东省自然科学基金-博士启动项目(2015A0303102262015.8-2018.8

8)广东省自然科学基金-自由探索项目(2016A0303138252016.6-2019.6

 

学术兼职

Chinese Medicine》《Chinese Herbal Medicines》期刊青年编委,《Diagnostics》期刊Guest Editor,广东省药理学学会抗炎免疫药理专业委员会委员;国家自然科学基金、广东省自然科学基金、浙江省自然科学基金、佛山市科技计划项目评审专家;Frontiers in PharmacologyFood FunctionOxidative Medicine and Cellular LongevityBMC Complementary Medicine and Therapies等期刊特约审稿人。

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