副研究员，硕士研究生导师，广东湛江海洋医药研究院技术平台负责人，。主要从事海洋药用活性成分发掘及其在抗衰老疾病的高值化利用。主持广东省高校优秀青年创新人才培养项目1项，广东省自然科学基金项目1项，广东省科技计划项目2项，广东省科技专项资金项目1项，湛江市竞争性财政资助项目2项；作为主要研究人员参研多项国家、省自然科学基金和科技计划项目；以第一发明人身份获国家发明专利授权2项和实用新型专利授权1项；以第一作者或通讯作者发表论文30余篇，其中10篇被SCI收录。参与的研究获得省科技进步三等奖及湛江市科技进步一等奖各1项。
近3年来承担项目
1.2019年广东省科技专项资金（“大专项+任务清单”乡村振兴战略专项）紫球藻多糖及藻胆蛋白复合制备关键技术研发与应用示范
2.2018年广东省自然科学基金项目，龙须菜非琼脂活性多糖依赖α-MSH/MC1R信号通路调控皮肤光老化性色素沉着的机制研究
3. 2017年湛江市科技计划项目龙须菜废碱液制备非琼胶活性多糖美白护肤产品关键技术的研发
近3年来发表SCI收录论文：
[1]Ke-feng Wu, Wei-Cheng Liang, Lu Feng, Jian-xin Pang, Mary Miu-Yee Waye, Jin-Fang Zhang, Wei-Ming Fu, H19 mediates methotrexate resistance in colorectal cancer through activating Wnt/β-catenin pathway. Experimental Cell Research, 350 (2017):312–317.
[2]KEFENG WU, XIANG GAO, BAOYAN SHI,SHIYU CHEN, XIN ZHOU, ZHIDONG LI,YUHONG GAN,LIAO CUI,JING XUAN KANG,WENDE LI* ,REN HUANG*, ENRICHED ENDOGENOUS n-3 POLYUNSATURATED FATTY ACIDS ALLEVIATE COGNITIVE AND BEHAVIORAL DEFICITS IN A MICE MODEL OF ALZHEIMER’S DISEASE. Neuroscience 333 (2016):345–355.
[3]KefengWu,Zhongqin Gong,LiyiZou,HuaYe,Changxiu Wang,Yangchun Liu,YanLiang,YanpingLi,JianweiReng,LiaoCui,YiLiu.Sargassum integerrimum inhibits oestrogen deficiency and hyperlipidaemia-induced bone loss by upregulating nuclear factor (erythroid-derived 2)-like 2 in female rats.Journal of Orthopaedic Translation, 2019, 19:106-117..
[3]Li Y, Li W, Deng W, Gan Y,Wu K*, Sun J*.Synergistic Anti-proliferative and Pro-apoptotic Activity of Ent-11α-hydroxy- 15-oxo-kaur-16-en-19-oic acid and Cisplatin in Human Non-small Cell Lung Cancer H23 Cells. Oncology letter. 2017 14(5):5347-5353.
[4] Guan T, Li T, Cai W, Huang D, Ouyang P, Wang Y, Chen H,Wu K*, Ma X*. HTR3A and HTR3E gene polymorphisms and diarrhea predominant irritable bowel syndrome risk: evidence from a meta-analysis. Oncotarget. 2017, 8(59): 100459-100468.
[5]Guan TM, Xiao S, Liu DC, Liao XH, Li WD,Wu KF*,Huang R.Protective effects of aqueous extract of wampee fruit against anti-tubercular drug-induced hepatotoxicity in rats. J Biol Regul Homeost Agents. 2019;33(1):175-181.
近3年来发表中文核心收录论文：
[1]廖雪华，甘育鸿，梅思，符伟玉，吴科锋*，李文德.黄皮果果核挥发油对小鼠黑色素瘤B16-F10细胞增殖和凋亡的影响[J].食品研究与开发, 2019,40(3):35-41.
[2]廖雪华，欧阳佩佩，叶华，王盼，吴科锋*，李文德.黄皮果果胶的提取工艺优化及理化性质分析[J].食品研究与开发, 2019, 38(2):177-181.
[3]符伟玉#，曾振飞，兰柳波，吴科锋*; RNA干扰Gα13对人卵巢癌HO-8910PM细胞侵袭转移的影响[J].药物分析杂志,2017,37(1):90-94.
[4]符伟玉#，兰柳波，李立，吴科锋*;辛伐他汀对人高转移卵巢癌HO-8910PM细胞Ras/MAPK/NF-κB通路的影响[J].实用医学杂志, 2016, 32(9):1398-1401.
